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作者用人羊水肺表面活性物质(PS)治疗一例肺透明膜病取得成功。PS剂量为150mg磷脂/kg,从气管插管一次滴入。临床症状,经皮测氧(TcPO_2)和吸入氧浓度(FiO_2)24h后明显好转,气道吸出物中的卵磷脂/鞘磷脂(L/S)比值、磷脂酰甘油(PG)和最低表面张力(γmin)逐渐恢复。肺部X线片原示毛玻璃样改变,PS治疗后3d明显改善,第6天病情基本恢复,最后痊愈出院。
The author of human pulmonary surfactant (PS) treatment of a case of hyaline membrane disease success. PS dose of 150mg phospholipid / kg, a drop from the endotracheal tube. Clinical symptoms, TcPO_2 and FiO 2 were significantly improved after 24 hours. The ratios of lecithin / sphingomyelin (L / S), phosphatidylglycerol (PG) and lowest surface tension (γmin) gradually recovered. Pulmonary X-ray showed the original glass-like changes, PS significantly improved 3d after treatment, the basic condition recovered on the 6th day, finally cured and discharged.