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用溴麦角环肽治疗18例帕金森病人,其中15例为用左旋多巴或复方左旋多巴后出现疗效减退、症状波动者。经治后13例症状改善,平均进步率31.3％(单纯用的3例为30.8％)。65岁以上老人疗效明显,病情较重者进步显著。对剂末现象有效,双手快复运动、震颤改善较好,而开-关现象无效。中国人用量较欧美人为小。副作用的发生个体差异较大,以小剂量开始,缓慢增量为宜。
18 patients with Parkinson’s disease were treated with bromocriptine, and 15 of them were treated with levodopa or compound levodopa with diminished efficacy and symptoms. After the treatment of 13 cases of symptoms improved, the average rate of progress was 31.3% (3 cases of pure use of 30.8%). Elderly people over the age of 65 significant effect, serious condition, significant progress. The agent at the end of the phenomenon of effective, fast hands and feet movement, tremor to improve better, while the on-off phenomenon is invalid. Chinese people use less than Europeans and Americans. The incidence of side effects of individual differences larger, beginning with a small dose, slow increment is appropriate.