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目的对淮安市新发现的HIV/AIDS首次CD4+T淋巴细胞计数进行分析,了解其免疫水平及疾病进展情况。方法收集淮安市2000-2014年报告的HIV/AIDS首次CD4+T淋巴细胞计数资料,分析其免疫水平,预测其疾病进程。结果 422例HIV/AIDS的首次CD4+T淋巴细胞均值为(322.81±245.81)个/μl,其中≤200个/μl占34.83%。年龄越大,首次CD4+T淋巴细胞计数均值越低(F=17.024,P<0.001),未婚、离异或丧偶者首次CD4+T淋巴细胞计数均值比已婚有配偶者高(F=12.091,P<0.001)。其他就诊者首次CD4+T淋巴细胞计数低于其他来源的HIV∕AIDS(χ2=83.076,P<0.001)。结论新发现的感染者中有1/3已经进入艾滋病期,应加强宣传干预,扩大检测,早期发现感染者,加强感染者随访监测,及时提供抗病毒治疗,提高其生存质量。
Objective To analyze the first CD4 + T lymphocyte count of newly discovered HIV / AIDS in Huai’an City, and to find out its immune status and disease progression. Methods The first CD4 + T lymphocyte count data of HIV / AIDS reported in Huai’an from 2000 to 2014 were collected to analyze the immune status and predict the progression of the disease. Results The mean of the first CD4 + T lymphocytes in 422 HIV / AIDS patients was (322.81 ± 245.81) / μl, of which ≤200 cells / μl accounted for 34.83%. The mean age of first CD4 + T lymphocyte count was lower (F = 17.024, P <0.001), and the mean of first CD4 + T lymphocyte count of unmarried, divorced or widowed was higher than that of married spouse (F = 12.091, P <0.001). Other clinicians had lower first-time CD4 + T-lymphocyte counts than HIV / AIDS from other sources (χ2 = 83.076, P <0.001). Conclusion One-third of the newly discovered HIV / AIDS patients have entered the HIV / AIDS phase. Publicity and intervention should be strengthened to increase detection, early detection of HIV infection, follow-up surveillance of HIV infection, timely delivery of anti-viral treatment and improvement of quality of life.