2型糖尿病引起的听力损害多表现为双侧对称性的感音神经性耳聋,以高频听力下降为主。2型糖尿病引起听力损害的报道逐年增多,但其发病机制尚不清楚,目前认为主要与非酶糖化、二酰甘油-蛋白激酶C、多元醇通路、炎症损伤、活性氧等有关,其共同特点是通过多种途径直接或间接使内耳神经及滋养神经的微血管受累,最终导致听力减退。 Type 2 diabetes caused by hearing loss and more performance for bilateral symmetrical sensorineural deafness, mainly to high-frequency hearing loss. However, the pathogenesis of type 2 diabetes mellitus has been increasing year by year, but the pathogenesis of type 2 diabetes mellitus is still unknown. It is currently believed to be mainly related to non-enzymatic glycation, diacylglycerol-protein kinase C, polyol pathway, inflammatory injury and reactive oxygen species. Is through a variety of ways directly or indirectly to the inner ear nerves and nourish the nerves of microvascular involvement, eventually leading to hearing loss.