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目的 :研究无水酒精非血管性介入治疗不正常子宫出血的价值。材料与方法 :无水酒精作用于子宫内膜 16h后 ,取离体子宫作病理观察。对 36例不正常子宫出血患者作宫腔造影 ,了解容量 ,注入等量无水酒精并抽出 ,反复 2～ 3次 ,每次在宫腔内保留 3～ 5min ,观察疗效。结果 :离体子宫巨检见内膜皱缩 ,灰褐色。镜下见内膜坏死脱落 ,动脉血栓形成 ,36例患者介入治疗后 ,88 9% (32 /36 )和 8 3 % (3/36 )分别在 2 4h和第 5天流血停止 ,5 5 6 % (2 0 /36 )恢复规律性月经周期 ,41 7% (15 /36 )月经量正常 ,38 9% (14 /36 )较正常月经量减少 ,4例复发作了第 2次介入治疗 ,6例绝经 ,1例手术切除 ,副作用有短时腹痛和局部灼热感。结论 :非血管介入治疗不正常子宫出血疗效可靠 ,方法简单 ,经济安全。
OBJECTIVE: To investigate the value of non-vascular alcohol-free intervention for the treatment of abnormal uterine bleeding. MATERIALS AND METHODS: After the action of anhydrous alcohol on the endometrium for 16h, the isolated uterus was taken for pathological observation. 36 cases of abnormal uterine bleeding in patients with uterine angiography, to understand the capacity, injection of equal amount of anhydrous alcohol and extracted, repeated 2 or 3 times, each retained in the uterine cavity 3 ~ 5min, observe the effect. Results: In vitro uterine girth see the endometrial shrinkage, taupe. Endoscopic necrosis and arterial thrombosis were seen in the endoscope. After the intervention of 36 patients, 88 9% (32/36) and 83% (3/36) stopped bleeding at 24 hours and 5 days respectively. % (20/36) regain regular menstrual cycle, 41 7% (15/36) menstruation normal, 38 9% (14/36) than the normal menstrual flow, 4 cases of recurrence of the second interventional treatment, 6 cases of menopause, 1 case of surgical resection, side effects of short-term abdominal pain and local burning sensation. Conclusion: Non-vascular interventional treatment of abnormal uterine bleeding is reliable, the method is simple and economical and safe.