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目的探讨地屈孕酮治疗先兆早期流产合并宫腔积血的临床效果。方法选择该院2016年1月-6月收治的398例先兆早期流产合并宫腔积血患者为研究对象,随机分为研究组(地屈孕酮组)和对照组(黄体酮组),对两组患者治疗后临床疗效、激素水平进行比较。结果研究组治疗后可明显改善患者临床症状,总有效率98.99%,优于对照组90.45%,差异有统计学意义(χ~2=55.932 0,P<0.01)。治疗后研究组血HCG(10 179.36±592.98)m U/ml和孕酮值(38.59±7.82)ng/ml明显高于对照组[(8 099.57±504.36)m U/ml、(29.79±6.13)ng/ml],差异有统计学意义(t=37.688 4、12.507 8,P<0.01)。结论地屈孕酮治疗先兆早期流产合并宫腔积血疗效显著,值得临床推广使用。
Objective To investigate the clinical effect of dydrogesterone in the treatment of threatened abortion combined with uterine hemorrhage. Methods A total of 398 patients with early abortion with uterine hemorrhage admitted from January 2016 to June 2016 in our hospital were enrolled in this study. Patients were randomly divided into study group (dydrogesterone group) and control group (progesterone group) Two groups of patients after treatment, clinical efficacy, hormone levels were compared. Results The study group could significantly improve the clinical symptoms of patients, the total effective rate was 98.99%, better than the control group 90.45%, the difference was statistically significant (χ ~ 2 = 55.932 0, P <0.01). The blood HCG (10 179.36 ± 592.98) mU / ml and progesterone (38.59 ± 7.82) ng / ml in the study group were significantly higher than those in the control group [(8 099.57 ± 504.36) mU / ml, (29.79 ± 6.13) ng / ml], the difference was statistically significant (t = 37.688 4,12.507 8, P <0.01). Conclusions Dydrogesterone treatment of threatened early abortion with uterine hemorrhage significant effect, it is worth promoting the use of the clinic.