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采用 AC→ ABC的合成策略 ,以α-环柠檬醛为 A环起始原料 ,通过与 C环化合物 8缩合、选择性还原及分子内环合得到关键中间体 1 1 ,再经过官能团修饰和转换 ,合成了 1 6 -羟基 -6 ,7-脱氢铁锈醇甲醚及其 3个类似物 .
Using AC → ABC synthetic strategy, the α-ring citral is the starting material of ring A, and the key intermediate 1 1 is obtained through the condensation with C ring compound 8, selective reduction and intramolecular cyclization. After the modification and conversion of the functional group , 16-hydroxy-6, 7-dehydropantarterol and its three analogs were synthesized.