最早确定人体癌肿中 RNA 肿瘤病毒的报告来自电子显微镜的研究,特别是 Dmoch-owski 等的研究。所描述的颗粒是十分稀少的,这些颗粒既未分离出,也未鉴定出其特性。此外,在当时未能利用有价值的生化和免疫学的技术,对新鲜肿瘤组织进行研究。因此,当时对于 RNA 肿瘤病毒和人体恶性病的关系的任何一种结论都受到了批评。 The earliest reports of RNA tumor viruses in human cancers came from electron microscopy studies, especially Dmoch-owski et al. The particles described are very scarce and the particles are neither isolated nor characterized. In addition, fresh tumor tissue was not studied at the time using valuable biochemical and immunological techniques. Therefore, any conclusion on the relationship between RNA oncoviruses and human malignancies was criticized at that time.