口眼干燥和关节炎综合征(Sjogern Syndrome)为一原因不明的罕见疾病,5～73岁均可发病。成人女性多见,儿童少见。现报告1例如下。女,9岁。因关节酸痛,腮腺肿1年9个月,发热、晨僵、关节肿半年,伴双眼异物感10天入院。体检:体温38.6℃,呈贫血貌,皮肤干燥,腮腺明显肿大。心率120次/分,心音略钝。腹软,肝肋下2.5cm,剑下5cm,脾肋下1.5cm、质均软、无压痛。四肢肌肉萎缩,双腕、膝、踝关节肿胀明显,轻度压痛、无红。指、趾关节呈梭状畸形。化验检查:血、尿常规 Dry mouth and arthritis syndrome (Sjogern Syndrome) is a rare unexplained disease, 5 to 73-year-old can be onset. More common in adult women, children rare. One report is as follows. Female, 9 years old. Due to joint pain, parotid gland swelling 1 year and 9 months, fever, morning stiffness, joint swelling for six months, with binocular foreign body sensation 10 days admitted. Physical examination: body temperature 38.6 ℃, anemia appearance, dry skin, parotid gland swelling. Heart rate 120 beats / min, heart sound blunt. Abdomen soft, liver ribs 2.5cm, 5cm under the sword, spleen rib 1.5cm, quality are soft, no tenderness. Limbs muscle atrophy, wrist, knee, ankle swelling significantly, mild tenderness, no red. Finger, toe joint was spindle deformity. Laboratory tests: blood, urine routine