论文部分内容阅读
目的分析前列腺12点穿刺中12点、10点、8点、改良及经典6点法的前列腺癌的检出率,探讨合理的个体化穿刺活检方案。方法回顾性分析我院行经直肠超声引导下前列腺12点系统性穿刺活检的病例共1 092例。分析不同PSA水平及前列腺大小时不同点数穿刺方案前列腺癌检出率的差异。结果共检出前列腺癌447例。总体前列腺癌检出率中12点穿刺法与10点差异无统计学意义,但P值接近临界值(P=0.065),12点与其他穿刺法差异均有统计学意义。前列腺最大横断面面积<15cm2时采用12点穿刺法与10点、8点、改良6点差异无统计学意义,与经典6点穿刺法的差异有统计学意义。PSA≥20ng/ml时,采用12点穿刺法与其他各种穿刺法之间的差异均无统计学意义。前列腺最大横截面面积≥15cm2及PSA<20ng/ml时12点与其他穿刺法差异均有统计学意义。结论对于前列腺最大横断面面积<15cm2的病例可采用改良6点穿刺法,PSA≥20ng/ml的病例可采用6点穿刺法,其余病例可采用12点穿刺法。
Objective To analyze the detection rate of prostate cancer at 12 o’clock, 10 o’clock, 8 o’clock, 12 o’clock and 12 o’clock in the prostate with modified and classic 6 o’clock method to explore a reasonable individualized biopsy program. Methods A retrospective analysis of our hospital under the guidance of rectal ultrasound 12 points of prostate biopsy cases of a total of 1 092 cases. Analysis of different PSA levels and prostate size of different punctate prostate cancer detection rate differences. Results A total of 447 cases of prostate cancer were detected. The overall prostate cancer detection rate of 12 points puncture method and 10 points was no significant difference, but P value close to the critical value (P = 0.065), 12 points and other puncture method differences were statistically significant. Prostate maximum cross-sectional area <15cm2 using 12-point puncture and 10 points, 8 points, 6 points to improve the difference was not statistically significant, and the classic 6-point puncture method was statistically significant. When PSA≥20ng / ml, there was no significant difference between 12-point puncture and other puncture methods. Prostate maximum cross-sectional area ≥ 15cm2 and PSA <20ng / ml at 12 o’clock and other puncture method were statistically significant. Conclusion The modified 6-point puncture method can be used for cases with the largest cross-sectional area of <15cm2. Six-point puncture can be used in patients with PSA≥20ng / ml, and 12-point puncture can be used in the remaining cases.