论文部分内容阅读
目的评价妊娠期宫颈上皮内瘤变(CIN)的转归及期待治疗的可行性及宫颈检查手段的安全可靠性。方法应用宫颈病变“三阶梯”诊断原则对1714例妊娠妇女进行宫颈病变筛查,并对诊断为CIN者进行孕期和产后的严密随访。结果 1714例妊娠妇女中,活检结果CINⅠ者26例,CINⅡ者7例,CINⅢ者3例,未发现浸润癌,对其进行严密随访,产后半年随诊结果为妊娠期CIN逆转率为50.0%,持续率为41.7%,进展率为8.3%;宫颈液基细胞学检查(TCT)、阴道镜及必要时的宫颈活检等检查手段用于妊娠妇女均未见明显并发症。结论妊娠期CIN的逆转率较高,多主张保守治疗,但应加强孕期及产后的严密随访;妊娠期进行宫颈的相关检查如TCT、阴道镜及活检等安全可靠,本研究可为制定妊娠期宫颈病变的诊治指南提供一定的循证医学证据。
Objective To evaluate the prognosis and prognosis of cervical intraepithelial neoplasia (CIN) in pregnancy and the safety and reliability of cervical examination. Methods A total of 1714 pregnant women were screened for cervical lesions using the principle of cervical lesions and “three steps”. The follow-up of pregnancy and postnatal follow-up of those diagnosed as CINs was performed. Results Among the 1714 pregnant women, 26 cases of CINⅠ, 7 cases of CINⅡ, 3 cases of CINⅢ, no invasive carcinoma were observed. The follow-up of 6 months postpartum was as follows: the CIN reversal rate in pregnancy was 50.0% The success rate was 41.7% and the rate of progress was 8.3%. There was no obvious complication in pregnant women tested by cervical liquid-based cytology (TCT), colposcopy and cervical biopsy when necessary. Conclusions The reversal rate of CIN during pregnancy is high, and many advocate conservative treatment, but should be strengthened during pregnancy and postnatal follow-up; cervical pregnancy related tests such as TCT, colposcopy and biopsy and other safe and reliable, this study may be the development of pregnancy Cervical lesions diagnosis and treatment guidelines provide some evidence-based medicine.