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目的观察小儿急性白血病时的血小板计数的变化。方法收集、整理、分析我院近15年内确诊为急性白血病的患儿在确诊时的血小板数等资料。结果收集小儿急性白血病84例,其中急性淋巴细胞白血病L1、L2型49例,急性非淋巴细胞白血病M2～M6型35例。血小板数在(7～274)×109/L,其中血小板数<50×109/L者56例(占66.67%),(50～100)×109/L者21例(占25.0%),≥100×109/L者7例(占8.33%)。结论本组小儿急性白血病的血小板数减少者占91.67%,不减少者占8.33%;在各亚型中以M3型血小板数减少较明显,均数为(30±16)×109/L。
Objective To observe the change of platelet count in childhood acute leukemia. Methods Collect, collate and analyze the number of platelets in the diagnosis of acute leukemia in our hospital in the past 15 years. Results Eighty-four cases of childhood acute leukemia were collected, including 49 cases of acute lymphoblastic leukemia L1 and L2 and 35 cases of M2 ~ M6 acute non-lymphocytic leukemia. The number of platelets was in the range of (7 ~ 274) × 109 / L, including 56 cases (66.67%) with platelets <50 × 109 / L and 21 cases (25.0%) with (50 ~ 100 × 109 / L in 7 cases (8.33%). Conclusions The reduction of platelet count in children with acute leukemia accounted for 91.67% and did not reduce in 8.33%. The reduction of M3 platelet count in each subtype was more significant (30 ± 16) × 109 / L.