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特应性皮炎的免疫学研究曾经主要限于体液免疫方面,后来开始研究本病的T细胞功能。作者们曾报告过一些相互矛盾的结果。最近研究表明,用T细胞致有丝分裂原ConA刺激淋巴细胞,可使之产生白细胞移动抑制因子(LMIF)。对某些细胞免疫低下的患者来说,如何杰金氏病、恶性淋巴瘤、原发性及继发性免疫缺陷等患者,检查LMIF活性是一种高敏感的测定法。不久前,这种检查法已用于研究特应性皮炎患者
The immunological study of atopic dermatitis was once mainly confined to humoral immunity, and later began to study the T cell function of this disease. The authors have reported some conflicting results. Recent studies show that leukocyte migration inhibitory factor (LMIF) can be produced by stimulating lymphocytes with T cell mitogen ConA. For some patients with immunocompromised cells, how to detect LMIF activity in patients with Parkinson’s disease, malignant lymphoma, primary and secondary immunodeficiency is a highly sensitive assay. Not long ago, this test has been used to study patients with atopic dermatitis