用庚型肝炎病毒（ＨＧＶ）人工感染恒河猴建立庚型肝炎动物模型在我国尚属首例。该实验用了５只恒河猴（２只感染，１只传代，２只对照）。本实验采用：逆转录ＰＣＲ法、间接ＥＬＩＳＡ法、酶速率法、肝组织光镜动态病理方法作为检测手段。其结果是：研究的２只猴都出现ＨＧＶ－ＲＮＡ、ＨＧＶ－ＩｇＧ阳性，持续时间５０周以上。感染第１０周肝组织出现急、慢性病毒性肝炎病变，并与人庚型肝炎病变基本相同，而血清转氨酶（ＡＬＴ）变化不明显。用感染后第７周猴子的阳性血清传代感染另一只猴，用同样的检测方法、内容，其结果与供血清猴的变化特征相同。实践证明，实验感染恒河猴建立庚型肝炎动物模型的研究首次获得成功 Artificial infection of Hepatitis G virus (HGV) to establish hepatic G-type animal model in our country is the first case. Five rhesus monkeys (2 infected, 1 passage, 2 controls) were used in this experiment. In this study, reverse transcription PCR, indirect ELISA, enzymatic rate method, light microscopy dynamic pathological method as a detection method. The result: HGV-RNA was present in both monkeys and HGV-IgG was positive for more than 50 weeks. In the 10th week of infection, acute and chronic hepatic lesions appeared in liver tissues, which were similar to those of human hepatitis G, but the changes of serum aminotransferase (ALT) were not obvious. The same test method and content were used to infect another monkey with positive sera from the positive sera of the 7th week after infection, and the result was the same as that of the serum monkey. Practice has proved that the experimental infection of rhesus monkeys to establish the animal model of hepatitis G for the first time successful