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据报道,AIDS患者罹患急性胰腺炎的危险性是正常人群的35～800倍,其原因主要为:(1)某些用于治疗HIV感染的药物对胰腺腺泡有直接毒作用;(2)免疫缺陷使之对胰腺炎易感;(3)某些HIV感染者滥用酒精,后者可导致酒精性胰腺炎。本文主要对HIV-1感染相关性急性胰腺炎的病因与流行病学进行文献分析。 流行病学AIDS患者约1/2经证实有胰腺组织异常,其中如脂肪组织坏死、纤维
It is reported that AIDS patients suffering from acute pancreatitis risk is 35 to 800 times the normal population, mainly because: (1) some of the drugs used to treat HIV infection have a direct toxic effect on pancreatic acini; (2) Immune deficiencies make it susceptible to pancreatitis; (3) Some people living with HIV abuse alcohol, which can cause alcoholic pancreatitis. This article mainly analyzes the etiology and epidemiology of acute pancreatitis associated with HIV-1 infection. Approximately one-half of epidemic AIDS patients are confirmed to have pancreatic tissue abnormalities, such as fatty tissue necrosis, fibrosis