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脑血管造影有继发神经系统并发症的危险性,而气泡栓塞可能促成这种危险。为检验这一假说,Makus 等应用多普勒超声监测了脑血管造影时是否有气泡栓塞发生,还对该现象作了动物模拟研究。对象为7例作脑血管造影的病人,女3,男4.35～78岁(平均58岁)。存股动脉插管和选择性颈总动脉脑血管造影时监测大脑中动脉的血流速率。所有病人都用非离子型造影剂碘苯六醇(iohexol),浓度为300mg/ml 和140mg/ml。对2只羊作了活体模拟研究。结果所有病例都成功地记录到大脑中动脉多普勒信号。在造影剂注入颈内或颈总动脉时用超
Cerebral angiography has the risk of secondary neurological complications, and embolism may contribute to this risk. To test this hypothesis, Makus et al. Used Doppler ultrasound to detect whether cerebral embolism occurred during cerebral angiography. Animal models of this phenomenon were also performed. The subjects were 7 patients with cerebral angiography, female 3, male 4.35 to 78 years (mean 58 years). Arterial cannulation and selective carotid artery cerebrovascular angiography to monitor the middle cerebral artery blood flow rate. All patients used nonionic contrast agent iohexol at concentrations of 300 mg / ml and 140 mg / ml. In vivo simulation of two sheep was conducted. Results All cases were successfully recorded in the middle cerebral artery Doppler signal. In the contrast agent into the neck or common carotid artery with ultra