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目的探讨支气管肺泡灌洗在难治性肺炎中的诊治价值。方法回顾性分析48例难治性肺炎患者，经纤维支气管镜支气管肺泡灌洗，并收集灌洗液送检细菌培养加药敏试验、涂片找霉菌及抗酸杆菌，再根据检验结果指导临床用药。结果48例难治性肺炎患者经纤维支气管镜行支气管肺泡灌洗诊治后，均获得良好的效果。结论经支气管肺泡灌洗对难治性肺炎患者的病原学诊断准确，治疗效果明显，是一种相对安全可靠易行方法。“,”Objective To investigate the diagnostic and therapeutic value of bronchoalveolar lavage in refractory pneumonia. Methods We retrospectively analyzed 48 cases diagnosed with refractory pneumonia. bronchoalveolar lavage fluid was collected by fiberoptic bronchoscopy for bacterial culture, susceptibility testing, detection of fungi and acid-fast bacillus in smears. Drug therapies were used according to these test results. Results All the 48 patients with refractory pneumonia were received good effects after performing fiberoptic bronchoscopy and bronchoalveolar lavage. Conclusion Patients with refractory pneumonia can obtain accurate diagnosis and effective treatment by fiberoptic bronchoscopy and bronchoalveolar lavage. The diagnostic and therapeutic method is safe, reliable and operational.