【摘 要】
：
采用3-羟基丁酸酯-3-羟基戊酸酯的共聚物(PHBV)与磷酸三钙(TCP)、羟基磷灰石(HA)、生物活性玻璃(BG)等进行复合, 获得了性能优良的生物活性骨组织工程支架材料和骨修复材料.
【机 构】
：
北京科技大学材料学学院,广州华南理工大学材料学院
论文部分内容阅读
采用3-羟基丁酸酯-3-羟基戊酸酯的共聚物(PHBV)与磷酸三钙(TCP)、羟基磷灰石(HA)、生物活性玻璃(BG)等进行复合, 获得了性能优良的生物活性骨组织工程支架材料和骨修复材料. 研究和比较了3种复合材料在体外模拟生理环境中发生的生物矿化反应, 对比了反应前后因矿化物的形成导致的表面微观形貌的变化, 通过检测反应液离子浓度的变化对不同材料的矿化过程和生物活性进行了定量表征. 研究结果表明, 3种复合材料在模拟生理溶液中发生生物矿化的过程和程度不同, 其中PHBV/BG的生物活性反应最为明显.
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