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目的:了解克林霉素的临床应用情况,为进一步提高临床合理用药水平提供参考。方法:采用前瞻性调查方法,分析252例279例次应用克林霉素的情况。结果:预防用药218例次,占78．14％;治疗用药61例次,占21．86％。不合理用药 139例次,占49．82％;合理用药73例次,占26．17％;基本合理用药67例次,占24．01％。其中预防用药的不合理比例 (51.83％)明显高于治疗用药(21．31％)。279例次中不良反应11例,发生率为3．94％。结论:应充分重视合理用药,尤其针对预防用药的合理性。药师的追踪与干预有利于临床的合理用药。
Objective: To understand the clinical application of clindamycin, to provide a reference for further improving the clinical reasonable dosage. Methods: A prospective investigation was conducted to determine the effect of clindamycin in 252 cases of 279 cases. Results: 218 cases of preventive medication, accounting for 78.14%; 61 cases of medication, accounting for 21.86%. 139 cases of irrational use of drugs, accounting for 49.82%; 73 cases of rational use of drugs, accounting for 26.17%; 67 cases of rational use of drugs, accounting for 24.01%. Among them, the unreasonable proportion of prophylaxis (51.83%) was significantly higher than that of medication (21.31%). There were 11 cases of adverse reactions in 279 cases, the incidence was 3.94%. CONCLUSION: Appropriate attention should be paid to the rational use of drugs, especially for the prevention of drug use. Pharmacist tracking and intervention is conducive to the rational use of clinical medicine.