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儿童的尿路感染(无尿路梗阻者)用适当的抗菌药物做短期治疗,根除感染并无困难,但预防再次感染却较困难。作者报导了在随机的45例(47次尿道感染发作)儿童,应用小剂量复方新诺明和呋喃(?)啶预防或不作预防的对照试验。以确定(1)预防尿道感染复发中预防剂的效力;(2)在停止抗菌素疗法后,长期用预防剂是否影响复发感染的类型。方法:作者报道了53例儿童,年龄2~12岁。细菌学证明有尿道感染及有正常的静脉尿道摄片和正常排尿的膀胱造影者作为研究对象。52倒尿路感染儿童用复方新诺明做短期治疗(7~10天),剂量为SMX20
Urinary tract infections (no urinary tract obstruction) in children with short-term treatment with appropriate antimicrobial drugs to eradicate infection without difficulty, but to prevent reinfection is more difficult. The authors report a controlled trial of prophylaxis or non-prophylaxis with a small dose of cotrimoxazole and furadine in children randomized to 45 patients (47 episodes of urinary tract infection). To determine (1) the efficacy of prophylaxis in the prevention of recurrence of urinary tract infections; (2) whether long-term prophylaxis affects the type of recurrent infection after stopping antibiotic therapy. Methods: The authors reported 53 children, aged 2 to 12 years old. Bacteriological evidence of urinary tract infection and normal venous urethra and normal voiding of the bladder contrast as a research object. 52 children with recurrent urinary tract infection with cotrimoxazole do short-term treatment (7 to 10 days), the dose of SMX20