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检测了６４例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）病人红细胞镁（Ｅ－Ｍｇ（２＋））浓度变化，同时观察了镁在体外对ＮＩＤＤＭ病人红细胞变形能力（ＥＤ）、红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性、Ｅ－Ｍｇ（２＋）和红细胞钙（Ｅ－Ｃａ（２＋））浓度的影响。结果显示，ＮＩＤＤＭ病ＨＥ－Ｍｇ（２＋）浓度较对照组明显降低（Ｐ＜０．００１），有血管病变者降低更明显。ＮＩＤＤＭ病人红细胞与镁共同孵育后，红细胞滤过指数（ＩＦ）、Ｅ－Ｃａ（２＋）明显降低，Ｅ－Ｍｇ（２＋）和红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性明显增高，与孵育前比较差异有极显著性（Ｐ＜０．００１），与对照组比较差异无显著性（Ｐ＞０．０５）。提示镁对改善ＮＩＤＤＭ病人血液流变学、减少血管病变的发生有重要意义。
The concentration of erythrocyte magnesium (E-Mg (2+)) in 64 patients with non-insulin dependent diabetes mellitus (NIDDM) was measured and the effect of magnesium on erythrocyte deformability (ED), erythrocyte membrane Na + -K + -ATPase Activity, E-Mg (2+) and erythrocyte calcium (E-Ca (2+)) concentrations. The results showed that the concentration of HE-Mg (2 +) in NIDDM patients was significantly lower than that in the control group (P <0.001), and those with vascular lesions were more obvious. After incubating erythrocytes and magnesium in NIDDM patients, the activity of E-Mg (2+) and erythrocyte membrane Na + -K + -ATPase were significantly decreased compared with that before incubation after erythrocyte filtration index (IF), E-Ca (P <0.001). There was no significant difference between the two groups (P> 0.05). Prompted magnesium to improve blood rheology NIDDM patients, reduce the occurrence of vascular disease is of great significance.