药品检验中,对于偏酸偏碱药物的菌检方法,部颁规定需用缓冲液稀释或用酸碱调节至中性后再进行检验。其目的是使药品中污染的微生物能在适宜的pH环境中生存、繁殖而被检出。该法由于忽略了培养基对药液的缓冲作用, Drug testing, for partial acid test method of partial alkali drugs, ministerial regulations need to be diluted with a buffer or acid-base adjusted to neutral after the test. Its purpose is to make the contaminated microorganisms in pharmaceuticals survive and reproduce in a suitable pH environment and be detected. The law due to neglect of the medium on the buffer solution,