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为探讨氟马西林对诊断及治疗药物中毒所致昏迷患者的有效性及安全性。31例疑苯二氮 类(BZs)药物中毒昏迷患者以氟马西林 0.2mg静脉注射,以后 0. 1mg·min~-1至总剂量达1mg或患者有反应。注射前后测定镇静程度,改善(2级为有反应。结果有反应者23例(A组)均为苯二氮类中毒,除6例因吸入性肺炎需继续治疗外,余均24 h内出院;无反应者8例(B组):仅有2例与苯二氮类中毒有关。全部病例均无明显药物不良反应。提示氟马西林可安全有效地用于诊断及治疗药物中毒所致昏迷。
To investigate the effectiveness and safety of flumacillin in patients with coma caused by the diagnosis and treatment of drug poisoning. Thirty-one patients with suspected benzene-diazepam (BZs) poisoning were given intravenous injection of flumacillin 0.2 mg after 0. 1mg · min ~ -1 to a total dose of 1mg or patients with reactions. Before and after the injection, the sedation level was measured and the level of sedation was improved (Level 2 was response.Results There were 23 responders (group A) were all benzodiazepine poisoning, except for 6 cases needing continuous treatment due to aspiration pneumonia, the remaining 24 hours Discharged in 8 cases (group B): only 2 cases were related to benzodiazepine poisoning.All cases showed no obvious adverse drug reactions, suggesting that flumacillin could be safely and effectively used in the diagnosis and treatment of drug poisoning To coma