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目的 :探讨卡前列甲酯栓预防和治疗产后出血的疗效。方法 :对 40 0例正常足月妊娠阴道分娩者 ,随机分为卡前列甲酯栓组 30 0例和缩宫素组10 0例。卡前列甲酯栓组在胎儿娩出后向阴道内置入卡前列甲酯栓 1mg ;缩宫素组在胎儿前肩娩出后静脉注射缩宫素 10IU。结果 :产后 2h平均出血量卡前列甲酯栓组为 138mL±s 2 6mL ,缩宫素组为 2 85mL± 60mL (P <0 .0 1)。产后出血发生率卡前列甲酯栓组为 4.0 % ,缩宫素组为 30 % (P <0 .0 1)。卡前列甲酯栓组不良反应轻微。结论 :卡前列甲酯栓预防和治疗产后出血是安全和有效的药物。
Objective: To investigate the curative effect of cardinal methylester suppository on prevention and treatment of postpartum hemorrhage. Methods: One hundred and forty cases of normal term pregnancy with vaginal delivery were randomly divided into 30 cases of cardinal methylester suppository group and 100 cases of oxytocin group. Card forefront of methyl ester suppository group after the baby was delivered to the vagina card into the forefront of methyl ester suppository 1mg; oxytocin group in the fetal anterior shoulder after delivery of oxytocin 10IU. Results: The mean amount of bleeding at 2h postpartum was 138mL ± s 2 for ketopamine suppository group and 285mL ± 60mL for oxytocin group (P <0.01). The incidence of postpartum hemorrhage was 4.0% in the cardinal methylester suppository group and 30% in the oxytocin group (P <0.01). Cardinal methylester suppository group mild adverse reactions. Conclusion: It is a safe and effective drug to prevent and treat postpartum hemorrhage by carbostylation suppository.