胰岛素是人体内唯一降低血糖的激素。对于胰岛素分泌或作用缺陷的糖尿病患者,外源性胰岛素对于其血糖控制和并发症防治具有重要作用。随着胰岛素制剂的不断发展和临床应用范围的日益扩大,胰岛素治疗在临床获益的同时伴随着治疗风险的出现,胰岛素使用时机的选择、剂型剂量的确定以及胰岛素使用所带来的相关问题需要引起临床医生的关注。胰岛素的发展历程20世纪20年代多伦多总医院开启了人类糖尿病胰岛素治疗的时代。早期胰岛素从动物胰腺中提 Insulin is the only hormone in the body that lowers blood sugar. For diabetic patients with insulin secretion or deficiency, exogenous insulin plays an important role in their glycemic control and prevention of complications. As insulin formulations continue to evolve and the range of clinical applications is expanding, the clinical benefit of insulin therapy is accompanied by the emergence of treatment risks, the timing of insulin use, the determination of dosage forms, and the associated problems associated with insulin use Aroused the concern of clinicians. Insulin Development Twentieth Century 20 Toronto General Hospital opened the era of insulin treatment of human diabetes. Early insulin is raised from the animal’s pancreas