本文提出了一条不以色胺为原料合成长春胺的关键中间体——高氯酸Wenkert氏烯胺的新途径。由于1-邻苯二甲酰亚胺基-4,5-辛二酮-4-苯腙(Ⅴ)的吲哚合成这一步收率很高,使这一途径成为合成1-正丙基-3,4-二氢-β-卡波林(Ⅶ)及Wenkert氏烯胺(Ⅹ)的较好方法。本文还利用红外光谱、质谱和核磁共振确定了1-邻羧基苯甲酰胺基-4,5-辛二酮-4-苯腙(Ⅳa)和1-正丙基-3,4-二氢-β-卡波林(Ⅶ)存在互变异构现象, In this paper, we propose a new route for the synthesis of Wenkert enamine from perchlorate, a key intermediate of vincamine, which does not use tryptamine. Due to the high yield of the indole synthesis of 1-phthalimido-4,5-octadione-4-phenylhydrazone (V), this route has led to the synthesis of 1-n-propyl- 3,4-dihydro-β-carbopol (Ⅶ) and Wenkert enamine (Ⅹ). In this paper, 1-O-carboxybenzamido-4,5-octanedione-4-phenylhydrazone (IVa) and 1-n-propyl-3,4-dihydro- β-Carbopol (Ⅶ) has the phenomenon of tautomerism,