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目的 探讨导致睡眠呼吸障碍患者睡眠中频繁发生觉醒的原因。方法 对因有白天过度困倦而就诊的 2 5例患者作全晚多导睡眠图 (PSG)检查和呼吸模式分析 ,并与 7名健康正常人对照。按国际标准人工判断觉醒。结果 上气道阻力综合征 (UARS)组 :10例 ,呼吸暂停 /低呼吸指数 (AHI)(2 5± 1 4)次 /h ,动脉血氧饱和度 (SaO2 ) <90 %累计时间 % (SLT90 % ) (0 1± 0 1) % ,觉醒指数 (ArI)(30± 16 )次 /h ;阻塞性睡眠呼吸暂停综合征 (OSAS)组 :15例 ,AHI(32 8± 19 1)次 /h ,SLT90 % (11 3±16 5 ) % ,ArI(35± 17)次 /h ;正常人组 :7名 ,AHI(5 9± 4 4)次 /h ,SLT90 % (0 2± 0 4) % ,ArI(13± 5 )次 /h。OSAS和UARS组的ArI无统计学差异 (H =0 49,P =0 48) ,均高于正常对照组的ArI (H分别为7 36和 5 2 2 ,P值分别为 0 0 0 1和 0 0 2 ) ,但UARS组AHI、SLT90 %明显低于OSAS组 (H >5 0 0 ,P <0 0 5 ) ,与正常组相近 (P >0 0 5 )。结论 睡眠时上气道吸气性阻力增高 ,是导致睡眠频繁觉醒的主要原因
Objective To explore the causes of frequent awakenings in sleep-induced respiratory disorder patients. Methods Twenty-five patients undergoing overtime sleep during the day were examined by polysomnography (PSG) and respiratory pattern analysis, and compared with 7 healthy controls. According to international standards of artificial judgment awakening. Results In the upper airway resistance syndrome (UARS) group, 10 patients had apnea / hypopnea index (AHI) of 25 ± 14 times / h and arterial oxygen saturation (SaO2) <90% (0 ± 1)%, SLI (30 ± 16) times / h, obstructive sleep apnea syndrome (OSAS) group: 15 cases and AHI (32 8 ± 19 1) times / h, SLT 90% (11 3 ± 16 5)%, ArI (35 ± 17) / h, normal control group 7, AHI 59 ± 4 4 / h, SLT 90% 4)%, ArI (13 ± 5) times / h. There was no significant difference in ArI between the OSAS and UARS groups (H = 0 49, P = 0 48), which were higher than those of the control group (H = 7 36 and 52 2, P 0,01 1 and However, the AHI and SLT90% of the UARS group were significantly lower than those of the OSAS group (H> 500, P <0.05), similar to the normal group (P> 0.05). Conclusion The obstruction of upper airway aspiration during sleep is increased, which is the main reason leading to frequent awakening of sleep