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目的探讨鼻塞持续呼吸道正压通气治疗新生儿呼吸衰竭的临床疗效。方法选取宁夏回族自治区妇幼保健院新生儿重症监护室2010年3月—2015年3月收治的65例新生儿呼吸衰竭患儿,采用随机数字表法将其分为观察组33例和对照组32例。两组均采取相同的综合治疗措施,观察组采用鼻塞持续呼吸道正压通气治疗,对照组采用面罩吸氧,对比观察两组患儿的临床治疗效果。结果治疗后,观察组患儿总有效率及显效率均高于对照组,差异有统计学意义(P<0.05);治疗24h后,观察组患儿动脉血氧分压(Pa O2)、动脉血氧饱和度(Sa O2)均高于对照组,二氧化碳分压(Pa CO2)低于对照组,差异有统计学意义(P<0.05)。结论与面罩吸氧疗法比较,鼻塞持续呼吸道正压通气治疗新生儿呼吸衰竭效果更显著,能够显著改善患儿的血气分析。
Objective To investigate the clinical efficacy of continuous positive airway pressure ventilation in the treatment of neonatal respiratory failure. Methods 65 neonates with respiratory failure from March 2010 to March 2015 in Ningxia Hui Autonomous Region Maternity and Child Health Hospital were randomly divided into the observation group (33 cases) and the control group (32) example. Both groups took the same comprehensive treatment measures, the observation group was treated with nasal continuous positive airway pressure ventilation, and the control group was treated with mask oxygen. The clinical effects of the two groups were compared. Results After treatment, the total effective rate and markedly effective rate in the observation group were significantly higher than those in the control group (P <0.05). After treatment for 24 hours, the PaO2 and arterial pressure Blood oxygen saturation (Sa O2) were higher than the control group, the partial pressure of carbon dioxide (Pa CO2) was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Compared with mask oxygen therapy, nasal continuous positive airway pressure therapy is more effective in neonatal respiratory failure and can significantly improve the blood gas analysis in children.