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氯硝安定(clonazepam)系一种新型苯二氮杂(艹卓)类抗惊厥药,临床上主要用于癫痫的治疗。作者自1990年试用该药治疗迟发性运动障碍(简称TD)34例,疗效满意,报道如下。一般资料:34例中,男23例,女11例;年龄18～56岁,平均33.6±10.2岁;病程1～21年,平均8.2±3.6年;引致TD的神经阻滞剂:吩噻嗪类19例,氟哌啶醇5例,两者联用7例,舒必利1例,五氟利多2例。TD出现前神经阻滞剂应用时间为0.5～15年,平均6 5±4.1年;TD病期为1个月～11年,乎均2.5±1.6年;TD类型:口-舌-颊三联
Clonazepam is a novel benzodiazepine anticonvulsant that is clinically used for the treatment of epilepsy. The author since 1990 trial of the drug treatment of tardive dyskinesia (referred to as TD) in 34 cases, the effect is satisfactory, reported as follows. General information: 34 cases, 23 males and 11 females; aged 18 to 56 years old, with an average of 33.6 ± 10.2 years; duration of 1 to 21 years, an average of 8.2 ± 3.6 years; leading to TD nerve blockers: phenothiazine 19 cases, haloperidol in 5 cases, the combination of the two in 7 cases, sulpiride in 1 case and pentaflumidono in 2 cases. TD before the application of nerve blockers for 0.5 to 15 years, an average of 6 5 ± 4. 1 years; TD period of 1 month to 11 years, an average of 2.5 ± 1.6 years; TD type: mouth - tongue - buccal triad