Objective:To investigate the studies on effects of Andrographis paniculata(A.paniculata) (Burm.f.) and Andrographis lineata(A.lineata) nees(Family:Acanthaeeae)extracts against two mosquitoes Culex quinquefasciatus(Cx.quinquefasciatus)(Say.) and Aedes aegypti(Ae.aegypti) (Linn.).Methods:The aqueous and petroleum ether extracts of two plant species.A.paniculata and A.lineate were examined against the larvae of,4.aegypti(L.) and Cx.quinquefasciatus with gradually increasing concenlration ie.from 50 to 200 ppm of solvent extracts and to test their activity in combination with each other.Results:In a 24 h bioassay experiment with plant extracts,highest mortalities were recorded at 200 ppm of concentrations for leaves of 4.lineta and A.paniculata individually.For combination effect,only 150 ppm of the mixture of solvent extracts of petroleum ether:aqueous(1:1) extracts showed 100%mortality after 24 h of exposure. Conclusions:The results show that,insecticides of plant combination is ecofriend and has better larvicidal activity compared to individual extracts. Objective: To investigate the studies on effects of Andrographis paniculata (Burk.f.) and Andrographis lineata (A.lineata) nees (Family: Acanthaeeae) extracts against two mosquitoes Culex quinquefasciatus (Cx.quinquefasciatus) (Say. ) and Aedes aegypti (Ae. aegypti) (Linn.). Methods: The aqueous and petroleum ether extracts of two plant species. A. paniculata and A. lineate were examined against the larvae of, 4. aegypti (L.) and Cx . quinquefasciatus with gradually increasing concenlration ie. from 50 to 200 ppm of solvent extracts and to test their activity in combination with each other. Results: In a 24 h bioassay experiment with plant extracts, highest mortalities were recorded at 200 ppm of concentrations for leaves of 4.lineta and A. paniculata individually. For combination effect, only 150 ppm of the mixture of solvent extracts of petroleum ether: aqueous (1: 1) extracts showed 100% mortality after 24 h of exposure. Conclusions: The results show that , insecticides of plant combination is ecofrien d and has better larvicidal activity compared to individual extracts.