作者曾报道在假孕大鼠一次注射PG_F(2a)能使黄体溶解和蜕膜瘤消退,如同时给予催乳素则能取消其溶黄体的作用。通过摘除垂体试验证明在妊娠前半期垂体是不可缺少的,在后半期胎盘就能独自代替垂体起作用。因而,作者想证明PGF_(2a)的抗生育作用是通过抑制垂体催乳素的产生呢?还是在卵巢水平上直接影响催乳素的作用? The authors have reported that a single injection of PG_F (2a) in a pseudopregnant rat luteal lysis and regression of decidual tumors, such as simultaneous administration of prolactin can cancel the role of luteal phase. By removing the pituitary test proved that in the first half of pregnancy, the pituitary gland is indispensable in the second half of the placenta can replace the pituitary function alone. Thus, the authors wish to demonstrate that the anti-fertility effect of PGF_ (2a) inhibits the production of pituitary prolactin, or does it directly affect the role of prolactin at ovarian level?