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目的观察比较生精片联合维参锌胶囊与他莫昔芬片治疗弱精症的临床效果。方法选取医院收治的弱精症患者128例作为研究对象,随机分为观察组和对照组,每组64例。对照组采用生精片联合维参锌胶囊进行治疗,观察组采用生精片联合他莫昔芬片进行治疗。对2组患者的精液进行测定,确定治疗前后精液内精子的浓度、精子总数、精子前向运动率及正常形态率。对2组患者治疗后的不良反应进行统计比较。结果治疗后,观察组精子浓度和精子总数均明显高于对照组(P<0.01);观察组精子前向运动率高于对照组(P<0.01)。2组治疗前后精子正常形态率比较差异均无统计学意义(P>0.05)。结论生精片联合他莫昔芬片治疗弱精症效果显著,能有效提高弱精症患者的精子浓度和活力,治疗方式简单,不良反应少,易被患者接受,具有临床应用及推广价值。
Objective To observe and compare the clinical effects of spermatogenesis tablets combined with weizhen zinc capsule and tamoxifen tablets in treating asthenospermia. Methods A total of 128 patients with asthenospermia admitted to hospital were selected as study subjects and randomly divided into observation group and control group with 64 cases in each group. The control group was treated with spermatozoon combined with vitamin Zinc capsule. The observation group was treated with spermatozoon combined with tamoxifen tablets. The sperm in two groups of patients were measured to determine the concentration of sperm in the semen before and after treatment, the total number of sperm, sperm motility and the rate of normal morphology. Two groups of patients after treatment of adverse reactions for statistical comparison. Results After treatment, the sperm concentration and the total number of sperm in the observation group were significantly higher than those in the control group (P <0.01). The forward sperm motility of the observation group was higher than that of the control group (P <0.01). There was no significant difference in sperm morphology between the two groups before and after treatment (P> 0.05). Conclusion SZT combined with tamoxifen tablets treatment of asthenospermia significant effect, can effectively improve the sperm concentration and vitality in patients with asthenospermia, simple treatment, fewer adverse reactions, easily accepted by patients, with clinical application and promotion of value.