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目的探讨术前经子宫动脉化疗及栓塞在治疗妇科恶性肿瘤的临床价值。方法采用Seldinger’s方法超选择性子宫动脉化疗及栓塞治疗妇科恶性肿瘤28例。结果宫颈癌16例,其中8例癌体较大,直径为4~6cm,5例伴有不同程度出血,经介入治疗后肿块体积缩小,出血停止;子宫内膜癌11例,其中2例Ⅰ期患者,术后病理切片见所有的癌细胞全部坏死,2例见大量坏死癌细胞;卵巢癌Ⅲa期1例,术后肿块缩小,腹水明显减少。结论术前超选择性子宫动脉化疗及栓塞可使妇科恶性肿瘤变性坏死、肿块体积缩小、出血减少,为后继治疗创造条件。
Objective To investigate the clinical value of preoperative uterine artery chemotherapy and embolization in the treatment of gynecological malignancies. Methods 28 cases of gynecological malignant tumor were treated with Seldinger’s method of superselective uterine artery chemotherapy and embolization. Results 16 cases of cervical cancer, including 8 cases of large cancers, diameter of 4 ~ 6cm, 5 cases with varying degrees of bleeding after the interventional treatment of the tumor volume decreased, bleeding stopped; 11 cases of endometrial cancer, of which 2 cases All of the patients and postoperative pathology showed all the necrosis of the cancer cells. A large number of necrotic cancer cells were seen in 2 patients. One patient with stage Ⅲa ovarian cancer was found to have a shrinkage of the tumor and a significant reduction of ascites. Conclusion Preoperative ultra-selective uterine artery chemotherapy and embolization can degeneration and necrosis of gynecological malignancies, tumor volume reduction, reduce bleeding, to create the conditions for the follow-up treatment.