各级疾病预防控制中心（CDC）作为疾病预防与控制的精锐部队，是筑牢疫情封堵之墙的核心主力军，在疫情应对过程中发挥着关键作用，然而此次新冠肺炎疫情应对也暴露出CDC系统建设亟待解决的一些问题：如能力建设缺乏系统性，应急队伍知识能力碎片化，流行病学调查手段老化，应急综合管理能力培训不足，以及偏重CDC应急设备、设施、技术等“硬资源”建设，而对风险预警和监测体系的不断更新以及各项网络和协同机制等“软资源”投入和建设相对不足等问题，成为制约CDC发挥更大效能的瓶颈和短板。为有效遏制本次疫情反弹并尽可能杜绝新的疫情再次发生，我们亟须对此次疫情应对和处置过程中的经验和教训进行深度反思和总结，并对关键问题和能力短板提出针对性的改进建议。“,”The Centers for Disease Control and Prevention (CDC), is an elite force for disease prevention and control, serving as the core force for blocking and contain the epidemic. Which plays a central role in fighting COVID-19 epidemic in China. However, during the process, its also exposed some problems: lack of comprehensive capacity building program, fragmented knowledge and skills, epidemiological investigation instrument is outdated, insufficient training on emergency management ability, emphasize investment in infrastructure, equipment and techniques but pay less attention to constantly updating the risk monitoring and alerting system as well as other important coordinating mechanisms, which will affect the well functioning of CDC system. In order to effectively curb the possible rebound of this epidemic and prevent the recurrence of new infectious diseases, we urgently need to reflect and summarize the experience and lessons of this outbreak response, and put forward more targeted policy options for future improvement.