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目的:探讨肝病患者检测血清甲胎蛋白(AFP)的意义。方法:检测200例肝病患者AFP定量并进行分析。结果:原发性肝癌阳性率79.5%,AFP平均为422.6μg/L。其次急性肝炎13.3%,慢性肝炎19.1%,重型肝炎28.6%,肝炎肝硬化25.0%。AFP的阳性率在原发性肝癌与病毒性肝炎比较有显著差异(P<0.01),各型肝炎比较差异无统计学意义(P>0.05)。结论:AFP诊断原发性肝癌有重要的临床意义,但有部分肝癌患者AFP水平不高。相反病毒性肝炎患者可出现一过性AFP增高,亦要警惕误诊。
Objective: To investigate the significance of serum AFP in liver disease patients. Methods: AFP was detected in 200 patients with liver disease and analyzed. Results: The positive rate of primary liver cancer was 79.5% and the average AFP was 422.6μg / L. Followed by acute hepatitis 13.3%, 19.1% of chronic hepatitis, severe hepatitis 28.6%, liver cirrhosis 25.0%. The positive rate of AFP in primary hepatocellular carcinoma was significantly different from that of viral hepatitis (P <0.01), but there was no significant difference in each type of hepatitis (P> 0.05). Conclusion: AFP diagnosis of primary liver cancer has important clinical significance, but some patients with liver cancer AFP level is not high. In contrast, patients with viral hepatitis may appear transient AFP increased, we must guard against misdiagnosis.