The cellular microenvironment modulates the role of PAI-1 and vitronectin in mediating cell-matrix i

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Plasminogen activator inhibitor-1 (PAI-1), a member of the serine protease inhibitor (serpin) superfamily of proteins, circulates in a complex with vitronectin. Furthermore, these two proteins are co-localized in the extracellular matrix (ECM) in many dif
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