目的观察肾小球肾炎合并急性间质性肾炎患者采用肾康注射液联合用药治疗的效果。方法 140例肾小球肾炎合并急性间质性肾炎患者,根据不同治疗方法分为对照组和观察组,各70例。对照组实施常规治疗,观察组在对照组治疗基础上联合肾康注射液、泼尼松、冬虫夏草等药物治疗。比较两组治疗的效果。结果两组患者治疗前血清肌酐、尿素氮、24 h尿蛋白含量水平比较差异无统计学意义(P>0.05);两组治疗后血清肌酐、尿素氮、24 h尿蛋白含量水平均优于治疗前,且观察组优于对照组,差异具有统计学意义(P<0.05)。观察组住院时间为(15.69±1.62)d,对照组住院时间为(22.63±1.45)d,观察组住院时间短于对照组,差异具有统计学意义(P<0.05)。观察组治疗总有效率为97.14%,高于对照组的84.29%,差异具有统计学意义(P<0.05)。结论给予肾小球肾炎合并急性间质性肾炎患者肾康注射液联合用药治疗,能够有效改善患者肾功能,可进一步推广应用。 Objective To observe the effect of using Shenkang injection in combination with drugs in patients with glomerulonephritis and acute interstitial nephritis. Methods One hundred and forty patients with glomerulonephritis and acute interstitial nephritis were divided into control group and observation group according to different treatment methods. The control group was given routine treatment. The observation group was treated with Shenkang injection, prednisone and Cordyceps sinensis on the basis of the control group. Compare the effects of treatment in both groups. Results There was no significant difference in serum creatinine, urea nitrogen and 24 h urinary protein levels between the two groups before treatment (P> 0.05). Serum creatinine, urea nitrogen and 24 h urinary protein levels in both groups were better than those before treatment Before, and the observation group was better than the control group, the difference was statistically significant (P <0.05). The length of stay in the observation group was (15.69 ± 1.62) d, the length of stay in the control group was (22.63 ± 1.45) days, and the length of stay in the observation group was shorter than that in the control group (P <0.05). The total effective rate of observation group was 97.14%, higher than 84.29% of control group, the difference was statistically significant (P <0.05). Conclusion The treatment of glomerular nephritis combined with Shen Kang injection in patients with acute interstitial nephritis can effectively improve renal function in patients with renal interstitial nephritis, which can be further popularized and applied.