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本文收集1931~1980年经病理组织学确诊的256例男性鼻咽癌病例,分析了他们远处转移的发生率和发生部位,其中63例(25%)进行过尸检。结果:(1)256例中93例(36%)有远处转移,其中61例是经临床和/或X线相诊断。63例尸检中,有32例(51%)有远处转移。随着病程的进展,远处转移增加;不同组织学类型的远处转移率没有明显差异。98%的远处转移均系在诊断后8年内发生。原发灶广泛者的远处转移率(44%)明显(P=0.0035)高于原发灶仅限于1~2个区域者(24%);
In this paper, 256 cases of nasopharyngeal carcinoma diagnosed by histopathology from 1931 to 1980 were collected. The incidence and location of distant metastases were analyzed. 63 of them (25%) were autopsy. Results: (1) Of the 256 cases, 93 (36%) had distant metastases, of which 61 were diagnosed clinically and / or radiographically. Of the 63 autopsies, 32 (51%) had distant metastases. With the progression of the disease, distant metastasis increased; different histological types of distant metastasis rate no significant difference. 98% of distant metastases occurred within 8 years after diagnosis. The distant metastasis rate (44%) was significantly higher in patients with extensive primary tumors (P = 0.0035) than those with primary tumors in only 1-2 regions (24%).