论文部分内容阅读
目的探讨以累及脑干为主的可逆性后部脑病综合征(posterior reversible encephalopathy syndrome,PRES)的临床特征及影像学表现,研究其发病机制。资料与方法回顾性分析6例以累及脑干为主的PRES患者的临床和影像学资料。6例中5例为原发性高血压患者,1例为慢性肾功能不全患者。临床主要表现为头晕、头痛及肢体活动障碍,无明显抽搐发作、视物障碍及神经系统局灶性定位体征。结果 MRI表现为脑干内异常信号,多累及延髓、小脑,也可合并幕上室旁白质病变。对症治疗后症状明显改善、影像学恢复正常提示其良性疾病过程。结论脑干型PRES作为一种影像学分布模式具有独特的临床表现形式。MRI对本病的诊断和鉴别诊断具有重要价值。
Objective To investigate the clinical features and imaging manifestations of posterior reversible encephalopathy syndrome (pred) involving the brain stem and to study its pathogenesis. Materials and Methods Retrospective analysis of clinical and imaging data of 6 patients with PRES involving brain stem. Five of six patients had essential hypertension and one had chronic renal insufficiency. Clinical manifestations of dizziness, headache and limb movement disorders, no obvious convulsions, visual disorders and focal neurological signs. Results MRI showed abnormal signals in the brainstem, involving multiple medulla oblongata and cerebellum, also can be associated with supratentorial white matter lesions. Symptomatic treatment significantly improved the symptoms, imaging returned to normal prompts the process of benign diseases. Conclusion Brainstem PRES has a unique clinical manifestation as an imaging distribution pattern. MRI diagnosis of the disease and differential diagnosis of great value.