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研究发现河豚卵巢提取物具有一定的免疫功能和生物活性。动物实验结果表明:注射不同浓度的提取物可明显增加小鼠脾脏和胸腺的重量(P<0.01);提高小鼠腹腔巨噬细胞吞噬率和吞噬指数(P<0.01)及提高由SRBC致敏的血凝素抗体的效价(P<0.01);对小鼠外周血清溶血素的生成无明显影响(P>0.05)。由此推测该提取物对免疫系统的不同环节.作用不同。且在一定剂量下对小鼠实体瘤S180的抑制率为45.8%。
The study found that pufferfish ovary extract has a certain degree of immune function and biological activity. The results of animal experiments showed that the injection of different concentrations of extracts can significantly increase the weight of spleen and thymus in mice (P<0.01); increase the phagocytic rate and phagocytic index (P<0.01) and increase in peritoneal macrophages of mice. The potency of hemagglutinin antibody sensitized by SRBC (P<0.01); no significant effect on peripheral serum hemolysin production in mice (P>0.05). This speculates that the extract has different links to the immune system. Different effects. And at a certain dose, the inhibition rate of solid tumor S180 in mice was 45.8%.