【摘 要】
：
目的 应用多b值DWI序列评估前列腺癌内分泌治疗后扩散与灌注信息的改变情况.方法 10例前列腺癌内分泌治疗后患者及12例前列腺癌患者被纳入研究.所有患者均经超声引导下前列腺
【机 构】
：
北京大学第一医院医学影像科,飞利浦医疗保健事业部
论文部分内容阅读
目的 应用多b值DWI序列评估前列腺癌内分泌治疗后扩散与灌注信息的改变情况.方法 10例前列腺癌内分泌治疗后患者及12例前列腺癌患者被纳入研究.所有患者均经超声引导下前列腺穿刺活检病理证实为前列腺癌,且在3.0T MR扫描仪进行了多b值DWI序列(b值分别为0,188,375,563,750 s/mm2)扫描.应用双指数模型(体素内不均一运动法)分析,计算并比较内分泌治疗组和未治疗组的癌区及非癌区的相对纯扩散值D,灌注分数f的变化.结果 内分泌治疗后癌区D值与f值分别为(1.16±0.08)×10-3mm2/s和(0.2±0.1)%.未治疗组癌区D值与f值分别为(0.76±0.05)×10-3mm2/s和(16.1±5.2)%.内分泌治疗后癌区的D值和f值与未治疗组癌区的D值和f值比较,差异均有显著统计学意义(P
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