胸膜覆盖在食管癌切除Ivor-Lewis术式中应用的随机对照试验

来源 :中国胸心血管外科临床杂志 | 被引量 : 0次 | 上传用户:psiteddd
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目的探讨胸膜覆盖在食管癌Ivor-Lewis术式中的优点。方法采用前瞻性研究方式,纳入在我院2013~2015年行传统Ivor-Lewis手术的食管中下段鳞癌患者200例。将患者随机分为两组:试验组在吻合口及下方的管状胃行胸膜覆盖,100例,男72例、女28例,年龄(54.76±6.62)岁;对照组不加行胸膜覆盖,100例,男66例、女34例,年龄(55.72±6.38)岁。主要对术后并发症及1年后复查的肺功能、吻合口平面压力、生活质量评分进行对比分析。结果两组患者术前一般情况及病理分期差异无统计学意义(P>0.05)。术后相关并发症发生率差异无统计学意义(P>0.05)。术后1年随访生存率差异无统计学意义(P>0.05)。试验组患者的生活质量高于对照组(P<0.05)。结论胸膜覆盖在食管癌Ivor-Lewis术式中是一个简单、安全、有效的技巧,能改善患者术后的生存质量。 Objective To investigate the advantages of pleural coverage in esophageal carcinoma Ivor-Lewis surgery. Methods A prospective study was conducted in 200 cases of squamous cell carcinoma in the lower esophagus undergoing traditional Ivor-Lewis surgery from 2013 to 2015 in our hospital. The patients were randomly divided into two groups: 100 cases, 72 males and 28 females, with an age of (54.76 ± 6.62) years. The control group had no pleural coverage and 100 Cases, 66 males and 34 females, age (55.72 ± 6.38) years old. Mainly on postoperative complications and 1 year after the review of lung function, anastomotic plane pressure, quality of life scores for comparative analysis. Results There was no significant difference between the two groups in preoperative general conditions and pathological stage (P> 0.05). There was no significant difference in the incidence of postoperative complications (P> 0.05). There was no significant difference in one-year follow-up survival rate (P> 0.05). The quality of life of the trial group was higher than that of the control group (P <0.05). Conclusion Pleural coverage is a simple, safe and effective technique in esophageal cancer Ivor-Lewis surgery, which can improve the postoperative quality of life of patients.
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