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吸入氯化铍中毒时,可引起急性中毒性肺水肿,为观察有机磷氨羧络合剂的疗效和从体内排除铍的功能,作者用体重24～25克雌小鼠340只,体重180～200克雌大鼠170只,经乙醚麻醉后,按大鼠0.15毫升/100克,小鼠0.03毫升/10克剂量,由气管注入氯化铍水溶液。染毒后10～15分钟,腹腔注射乙二胺二异丙基膦酸二钠盐和二乙基三胺五甲基膦酸钙钠盐。氨羧络合剂的疗效是按中毒急性阶段动物的存活率和肺水肿程度进行评价。另外,应用放射性同
Inhaled beryllium chloride poisoning can cause acute toxic pulmonary edema, to observe the efficacy of organophosphamide carboxylase complex and the role of beryllium excluded from the body, the author with a body weight of 24 to 25 grams of female mice 340, weighing 180 ~ 170 g of 200 g female rats were anesthetized with diethyl ether and injected with a beryllium chloride aqueous solution through the trachea at a rate of 0.15 ml / 100 g for rats and 0.03 ml / 10 g for mice. Ten to fifteen minutes after exposure, intraperitoneal injection of ethylenediamine diisopropylphosphonic acid disodium salt and diethyltriamine pentamethylphosphonic acid sodium salt. The efficacy of the Ammonia-Carboxylic Complex is evaluated by the survival rate of the animals in acute phase of poisoning and the degree of pulmonary edema. In addition, the same applies to radioactive