论文部分内容阅读
目的研究老年结直肠癌患者肿瘤相关性贫血发生情况,探讨肿瘤病理分期与贫血间的关系,为肿瘤相关性贫血的干预提供依据。方法选择湖北医药学院附属太和医院2013年4月—2014年4月收治的老年结肠癌患者245例作为研究对象,收集患者Hb水平,采用Dukes分期法收集患者的肿瘤分期情况。贫血诊断标准采用美国国立肿瘤研究所贫血分级标准,贫血细胞形态学分类参照《内科学》第8版教材。结果 245名老年结直肠癌患者Hb平均值为(108.16±22.02)g/L,贫血发生率为54.3%(133/245),不同性别患者肿瘤相关性贫血发生率差异无统计学意义(P>0.05),不同病理分期患者贫血发生率差异有统计学意义(P<0.05);不同病理分期患者贫血类型差异有统计学意义(P<0.05);不同肿瘤部位患者贫血发生率差异有统计学意义(P<0.05)。结论老年结直肠癌患者贫血发生率较高,贫血的发生与肿瘤病理分期密切相关,抗肿瘤治疗的同时应积极干预患者贫血状态,提高患者的机体抵抗力与生活质量。
Objective To study the incidence of tumor-associated anemia in elderly patients with colorectal cancer and to explore the relationship between tumor pathological stage and anemia and to provide basis for the intervention of anemia associated with cancer. Methods A total of 245 elderly patients with colon cancer who were treated in Taihe Hospital Affiliated to Hubei Medical College from April 2013 to April 2014 were selected as study subjects. Hb levels were collected and staging was performed by Dukes staging. Anemia diagnostic criteria using the National Institute of Cancer anemia grading standards, anemia, cell morphology, refer to the “Science” eighth edition textbook. Results The average Hb in 245 elderly patients with colorectal cancer was (108.16 ± 22.02) g / L, and the incidence of anemia was 54.3% (133/245). There was no significant difference in the incidence of tumor-related anemia between different sexes (P> 0.05). There was significant difference in the incidence of anemia among different pathological stages (P <0.05). There was significant difference in the type of anemia between different pathological stages (P <0.05), and the difference of anemia among different tumor sites was statistically significant (P <0.05). Conclusion The incidence of anemia in elderly patients with colorectal cancer is high. The incidence of anemia is closely related to the pathological stage of the tumor. Anti-tumor therapy should be actively involved in the treatment of patients with anemia and improve the body’s resistance and quality of life.