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雪莲是菊科青木香属多年生草本植物。古籍记载,有除寒、状阳、调经、止血等作用。近年研究证明雪莲煎剂有抗炎、加强蟾蜍心肌收缩力、降低兔血压、抑制兔回肠活动、兴奋离体和在体兔子宫、终止小鼠和家兔早期妊娠等作用。我院化学教研室从雪南省德钦县产的水母雪莲花(Saussurea medusa Maxim.)中分离出多糖单一组分,已证明对小鼠有明显的终止妊娠作用。本文研究了雪莲多糖(简称SPS)对各期离体大鼠子宫的作用。并观察前列腺素E_2(PGE_2)和消炎痛对雪莲多糖兴奋子宫作用的影响。
Saussurea is a genus of Asteraceae perennial herb. Ancient records, in addition to cold, Yang shape, menstruation, bleeding and other effects. In recent years, studies have shown that snow lotus decoction has anti-inflammatory, strengthen toad myocardial contractility, reduce rabbit blood pressure, inhibit ileum activity, excited in vitro and in vivo in the rabbit uterus, termination of early pregnancy in rabbits and rabbits and so on. Our chemistry department has isolated a single component of polysaccharides from Saussurea medusa Maxim., A native of Deqin county in the province of Seychelles, and has shown significant termination of pregnancy in mice. In this paper, the effect of snow lotus polysaccharide (SPS) on the uterus of isolated rat in each phase was studied. The effects of prostaglandin E_2 (PGE_2) and indomethacin on the excitatory uterus of snowdrop polysaccharide were observed.