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近年生物技术的迅猛进展使人们对肿瘤免疫机制的认识有了很大提高,肿瘤免疫疗法也相应得到发展。生物效应调节剂(BiologicalResponse Modifiers,BRM)是指影响宿主与肿瘤之间相互关系的物质,凡能改善宿主对肿瘤细胞的生物效应而产生治疗效果的药剂或方法都可称为BRM,因此BRM 是包括免疫疗法在内而范围更广的一种治疗方法,在此概念指导下,BRM 的研究已引起各国的广泛注意。在已报道的BRM 中,最引人注意的是淋巴细胞
The rapid development of biotechnology in recent years has made people’s understanding of the mechanism of tumor immunity greatly improved, and tumor immunotherapy has also been correspondingly developed. Biological response modifiers (BRMs) refer to substances that affect the relationship between the host and the tumor. Any agent or method that can improve the host’s biological effect on tumor cells and produce a therapeutic effect can be called a BRM, so the BRM is A wider range of therapeutic methods including immunotherapy, under the guidance of this concept, BRM research has attracted wide attention of countries. Among the reported BRMs, the most noticeable is lymphocytes.