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目的:探讨病毒感染后嗅觉障碍(PVOD)患者的临床特征。方法:收集并分析2009-07-2015-01期间就诊的连续141例PVOD患者的病例信息,包括调查问卷获取一般信息及发病症状,主观嗅觉心理测试采用Sniffin’Sticks Test。结果:回顾性分析连续就诊的141例PVOD患者,男女比例为1.0:2.3,嗅觉障碍严重程度在男女间无差别(χ~2=0.05,P>0.05)。患者年龄在30~40岁、50~60岁有集中的趋势。鼻塞、鼻涕、喷嚏是PVOD最常见的鼻部症状,咽痛、咳痰、咳嗽是最常见的其他症状。结论:大样本PVOD患者的临床特点分析进一步提示PVOD的发生可能和性别、年龄等因素有关,但目前我们对这种复杂疾病的认识十分有限,需要进一步的研究。
Objective: To investigate the clinical characteristics of patients with olfactory disorder (PVOD) after viral infection. Methods: The data of 141 consecutive PVOD patients who were treated during 2009-07-2015-01 were collected and analyzed. The questionnaires were used to obtain general information and symptom onset. The subjective smell test was conducted using Sniffin ’Stuy Test. Results: A retrospective analysis of 141 consecutive patients with PVOD patients, male to female ratio of 1.0: 2.3, the severity of the olfactory disorder was no difference between men and women (χ ~ 2 = 0.05, P> 0.05). Patients aged 30 to 40 years old, 50 to 60 years old have a concentration trend. Nasal congestion, nasal discharge, sneezing is the most common nasal symptoms of PVOD, sore throat, expectoration, coughing is the most common other symptoms. Conclusion: The analysis of clinical features of large sample of patients with PVOD further suggests that the occurrence of PVOD may be related to gender, age and other factors, but at present our understanding of this complex disease is very limited and needs further study.