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翼状胬肉是眼科常见病,其病因及发病机制有多种不同的解释,而确切机制尚不清楚,但多数研究表明,翼状胬肉的主要诱因是环境因素,紫外线过强刺激与翼状胬肉的发生密切相关,还有如眼部长期受到风沙、烟尘、热、花粉等过度刺激,遗传因素、营养缺乏、泪液分泌不足、过敏反应及解剖因素等等,种种诱因使角膜缘上皮屏障破坏,继而结膜变性与增生而发生本病,在此过程中,免疫因素参与的成纤维细胞转化起重要作用。对翼状胬肉的病因及发病机制进行综述。
Pterygium is a common ophthalmology, the etiology and pathogenesis have a variety of different explanations, and the exact mechanism is not yet clear, but most studies have shown that the main incentive for pterygium is environmental factors, excessive UV stimulation and pterygium There are also closely related to the occurrence of the eye, such as the eye by the sand, dust, heat, pollen and other over-stimulation, genetic factors, nutritional deficiencies, lack of tear secretion, allergic reactions and anatomical factors, all kinds of incentives to damage the limbal epithelial barrier, Conjunctival degeneration and proliferation of the disease occurs, in the process, the immune factors involved in the transformation of fibroblasts play an important role. The etiology and pathogenesis of pterygium were reviewed.