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国内外对抽动障碍的研究涉及神经生化、神经心理学、神经影像学等多个领域。近年来磁共振成像研究为抽动障碍病因学研究提供了较多证据。结构磁共振研究发现基底核结构显著异常,额叶、枕叶皮质特别是感觉运动皮质变薄等。而功能磁共振方面则发现皮质-纹状体-丘脑-皮质环路功能异常,胼胝体纤维连接程度下降等。现就抽动障碍与磁共振成像、药物干预之间的关系进行综述。
Domestic and foreign research on tic disorder involves neurobiochemistry, neuropsychology, neuroimaging and other fields. In recent years, magnetic resonance imaging study for the etiology of tic disorder provides more evidence. Structural magnetic resonance imaging found that the structure of basal ganglia was significantly abnormal, frontal, occipital cortex, especially sensory motor cortex thinning. The functional magnetic resonance was found in the cortex - striatum - thalamic - cortical ring dysfunction, corpus callosum fiber connectivity decreased. Now on the tic disorder and magnetic resonance imaging, the relationship between drug intervention are reviewed.