通过Ｌ３（３）正交试验，对双氧水氧化法合成氧化叔胺的工艺条件进行了优化研究。测试了反应温度、反应时间和双氧水过量比对产物得率的影响，从而获取了在有机酸催化作用下的最佳工艺条件为：反应温度７５℃，反应时间１２ｈ，双氧水过量１５％。在此条件下重复试验，均可使最终氧化叔胺收率≥９５％，从而为该表面活性剂的工业生产提供了可靠的工艺参数。 Through the orthogonal experiment of L3 (3), the process conditions for the synthesis of tertiary amine oxides by hydrogen peroxide oxidation were optimized. The effects of reaction temperature, reaction time and excess ratio of hydrogen peroxide on the yield of the product were tested. The optimum conditions were as follows: reaction temperature 75 ℃, reaction time 12h, hydrogen peroxide 15%. Repeated experiments under these conditions, can make the final yield of tertiary amine oxide ≥ 95%, which provides the industrial production of the surfactant provides a reliable process parameters.